JACN Did you know that you can get alerts when a new issue is online?
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Martinez, J. A.
Right arrow Articles by Urbistondo, M. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Martinez, J. A.
Right arrow Articles by Urbistondo, M. D.

Journal of the American College of Nutrition, Vol 13, Issue 2 192-197, Copyright © 1994 by American College of Nutrition

JOURNAL ARTICLE

Effects of pharmacological therapy on anthropometric and biochemical status of male and female institutionalized psychiatric patients

J. A. Martinez, J. J. Velasco and M. D. Urbistondo
Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain.

OBJECTIVE: The pathophysiological condition and potential drug interactions may influence nutritional status. Therefore, the aim of this study was to determine, separately in male and female schizophrenic subjects, the influence of neuroleptic treatment on different indices of nutritional status. DESIGN: The survey was conducted at a 750-bed mental hospital in 311 custodial care patients, where anthropometric and hematological estimations were measured. RESULTS: In the present study, prevalence of obesity, (assessed by weight-for-height) increased by 10% in males and 18% in females on neuroleptic medication as compared to psychotropic-free schizophrenic subjects. Those taking neuroleptic medication also had larger fat and protein body compartments. Statistical differences between the groups (controls vs neuroleptics) were found for triceps skinfold and arm-muscle circumference as indices of body composition, being more marked in female patients. Neuroleptic administration was associated with changes in iron status, plasma protein, high-density lipoprotein cholesterol and triglycerides in males, while only plasma protein levels were affected in the female schizophrenic group under antipsychotic therapy. CONCLUSION: This study provides further evidence of adverse consequences of neuroleptic drugs on anthropometric and biochemical markers of nutritional status, and also shows differences between male and female patients in their response to psychotropic medications.


This article has been cited by other articles:


Home page
 J PsychopharmacolHome page
C. Bushe and C. Paton
The potential impact of antipsychotics on lipids in schizophrenia: is there enough evidence to confirm a link?
J Psychopharmacol, November 1, 2005; 19(6_suppl): 76 - 83.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1994 by the American College of Nutrition.