Journal of the American College of Nutrition, Vol 13, Issue 6 559-564, Copyright © 1994 by American College of Nutrition

JOURNAL ARTICLE

The role of vitamin D in toxic metal absorption: a review

J. Moon
National College of Naturopathic Medicine, Portland Oregon 97216.

Vitamin D increases intestinal calcium and phosphate absorption. Not so well known, however, is that vitamin D stimulates the co-absorption of other essential minerals like magnesium, iron, and zinc; toxic metals including lead, cadmium, aluminum, and cobalt; and radioactive isotopes such as strontium and cesium. Vitamin D may contribute to the pathologies induced by toxic metals by increasing their absorption and retention. Reciprocally, lead, cadmium, aluminum, and strontium interfere with normal vitamin D metabolism by blocking renal synthesis of 1,25-dihydroxyvitamin D. This is the first review of the role of the vitamin D endocrine system in metal toxicology.

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