JACN Did you know that you can get alerts when a new issue is online?
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hammami, M.
Right arrow Articles by Koo, W. W.K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hammami, M.
Right arrow Articles by Koo, W. W.K.
Journal of the American College of Nutrition, Vol. 21, No. 4, 328-332 (2002)
Published by the American College of Nutrition

Phantoms for Cross-Calibration of Dual Energy X-ray Absorptiometry Measurements in Infants

Mouhanad Hammami, MD, Jean-Charles Picaud, MD, PhD, Christoph Fusch, MD, Elaine M. Hockman, PhD, Jacques Rigo, MD and Winston W.K. Koo, MBBS, FACN

Departments of Pediatrics, Obstetrics and Gynecology (M.H., W.W.K.K.), Wayne State University, Detroit, Michigan
Computing and Information Technology (E.M.H.), Wayne State University, Detroit, Michigan
Neonatal Unit and Human Nutrition Research Center, University of Lyon, Lyon, FRANCE (J.-C.P.)
Neonatal Unit, University Children’s Hospital, Greifswald, GERMANY (C.F.)
Neonatal Unit, University of Liege, Liege, BELGIUM (J.R.)

Address reprint requests to: Dr. Winston Koo, Department of Pediatrics, Hutzel Hospital, 4707 St Antoine Blvd, Detroit, MI 48201. E-mail: wkoo{at}wayne.edu

Objective: To test the suitability of phantoms to cross-calibrate body composition measurements in small subjects among different dual energy X-ray absorptiometry (DXA) instruments.

Methods: A set of four phantoms with total weights 1520g, 3140g, 4650g and 7490g were made with low cost and easily available materials. Each phantom was made from assembling polyethylene bottles (100 to 1000 mL) filled with either pure olive oil or electrolyte solution in different combinations, and borosilicate tubes (3 and 5 mL) and flexible polypropylene tubing filled with calcium carbonate. Triplicate measurements of each of the four phantoms were performed with three pencil beam densitometers made by the same manufacturer (Hologic Inc., Waltham, MA): two QDR 2000 (University of Liege, Liege, Belgium, and Wayne State University, Detroit, Michigan) and a QDR1500 (University Children’s Hospital, Greifswald, Germany) using infant whole body-scanning mode and analyzed with software V5.73P.

Results: DXA measured total weight, or bone, lean and fat masses, from one center were highly predictive of DXA measurements from the other centers with an adjusted r2 of 0.94 to 1.00, p < 0.001. This was the case whether the measurements from single scan or from average of triplicate scans were used in the analysis.

Conclusions: Systematic corrections, in the form of linear transformations, are possible to allow comparison of clinical data generated from different centers. Different size phantoms can be made to accommodate the varying range of weights and body composition of study subjects.

Key words: phantom, body composition, fat, lean, bone, infant




This article has been cited by other articles:


Home page
 Am. J. Clin. Nutr.Home page
W. W. Koo, M. Hammami, and E. M Hockman
Interchangeability of pencil-beam and fan-beam dual-energy X-ray absorptiometry measurements in piglets and infants
Am. J. Clinical Nutrition, August 1, 2003; 78(2): 236 - 240.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2002 by the American College of Nutrition.