JACN Did you know that you can get alerts when a new issue is online?
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Klevay, L. M.
Right arrow Articles by Aviv, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Klevay, L. M.
Right arrow Articles by Aviv, A.
Journal of the American College of Nutrition, Vol. 26, No. 2, 103-110 (2007)
Published by the American College of Nutrition

Renal And Gastrointestinal Potassium Excretion In Humans: New Insight Based On New Data And Review And Analysis Of Published Studies

Leslie M. Klevay, MD, John D. Bogden, PhD, Mordechay Aladjem, MD, Harold H. Sandstead, MD, Francis W. Kemp, BS, Wenjie Li, MD, Joan Skurnick, PhD and Abraham Aviv, MD

Hypertension Research Center of the Cardiovascular Research Institute of New Jersey (M.A., A.A.)
Department of Preventive Medicine and Community Health (J.D.B., F.W.K., W.L., J.S.), UMDNJ, New Jersey Medical School, Newark, New Jersey
USA Department of Agriculture, Agricultural Research Service, Grand Forks, Human Nutrition Research Center, Grand Forks, North Dakota (L.M.K.)
Department of Preventive Medicine and Community Health, University of Texas, Medical Branch Galveston, Texas (H.H.S.)

Address reprint requests to: John D. Bogden, PhD, Room F-506, Preventive Medicine & Community Health, UMDNJ, NJ Medical School, 185 South Orange Ave, Newark, NJ, 07103. E-mail: bogden{at}umdnj.edu

Objectives: Little is known about the relationship between the renal and gastrointestinal excretion of potassium in humans. This information is important in light of strong associations of potassium intake with hypertension and occlusive stroke.

Methods: We determined the relationship between fecal and urinary excretion of potassium under both fixed and variable potassium intakes using our unpublished archival data and published data of others. Twenty-five subjects were evaluated.

Results: On a fixed, low oral potassium intake (61.2 ± 4.7 mmol/day; mean ± SD), there was an inverse relationship between fecal and urinary potassium excretion (r = –0.66, p = 0.040). In studies in which potassium intake varied between 61–135 mmol/day, fecal and urinary potassium excretions were positively correlated (r = 0.58, p = 0.024). Considerable within-and-between-subject variation was observed in the relationship between fecal and urinary potassium excretion.

Conclusions: Inter-individual variation in fecal potassium excretion may arise from both variation in dietary potassium intake and intrinsic individual differences in the renal versus gastrointestinal handling of potassium.

Key words: potassium, steady-state, kidney, intestine, urine, feces






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2007 by the American College of Nutrition.