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Journal of the American College of Nutrition, Vol 9, Issue 2 97-100, Copyright © 1990 by American College of Nutrition

JOURNAL ARTICLE

Methionine metabolism in the Buffalo rat following ethanol feeding

A. J. Barak, H. C. Beckenhauer and D. J. Tuma
Liver Study Unit, Veterans Administration Medical Center, Omaha, Nebraska 68105.

Earlier studies have demonstrated that the Buffalo strain rat may have a defect in the process of methylneogenesis or lack the methyl-transfer enzyme system in the liver involved in methionine biosynthesis. The results of this study demonstrate that the enzyme systems responsible for methionine formation are present in the Buffalo rat and that these systems respond to ethanol feeding in a manner similar to that already shown in the Sprague-Dawley animal. These findings suggest that the previously described defect in methionine metabolism of the Buffalo rat may lie within the mechanism of methylneogenesis.




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Copyright © 1990 by the American College of Nutrition.