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Methodologies for Using Stable Isotopes to Assess Magnesium Absorption and Secretion in Children

USDA/ARS Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas

View larger version (14K): [in a new window]   Fig. 1. Time-dependent change in cumulative fractional absorption of magnesium after dosing with 26Mg orally and 25Mg intravenously. Data shown are for the mean ± SD of the total fraction of the cumulative absorption fraction measured after 120 hours at each 8-hour interval up to 120 hours. The total mean absorption fraction at 120 hours was 44% [7]. For example, the first point shows that at 8 hours after completion of 26Mg dosing, the mean fractional absorption was 64% of this 44%. Absorption was 95% complete after 72 hours.

View larger version (15K): [in a new window]   Fig. 2. The relationship between dietary magnesium intake and urinary magnesium excretion: y = 0.35*x + 0.18, r = 0.47, p = 0.02.

View larger version (14K): [in a new window]   Fig. 3. The relationship between dietary magnesium intake and endogenous fecal magnesium excretion: r = 0.08, p = 0.69.