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Day-to-Day Consistency in Amount and Source of Carbohydrate Intake Associated with Improved Blood Glucose Control in Type 1 Diabetes

Thomas M.S. Wolever, MD, PhD, FACN,, Safa Hamad, MSc, Jean-Louis Chiasson, MD, Robert G. Josse, MD,, Lawrence A. Leiter, MD,, N. Wilson Rodger, MD, Stuart A. Ross, MD and Edmond A. Ryan, MD

Department of Nutritional Sciences, University of Toronto, Division of Endocrinology and Metabolism, St. Michael’s Hospital (T.M.S.W., R.G.J., L.A.L.), Toronto, Onario, Research Centre, CHUM
Clinical Nutrition and Risk Factor Modification Centre, St. Michael’s Hospital (T.M.S.W., S.H., R.G.J., L.A.L.), Toronto, Onario, Research Centre, CHUM
Hôtel-Dieu de Montreal Hospital, Montreal, Quebec (J.-L.C.), CANADA
St. Joseph’s Health Centre, University of Western Ontario, London, Ontario (N.W.R.), CANADA
Diabetes Education and Research Centre, Calgary (S.A.R.), CANADA
Heritage Medical Research Centre, University of Alberta, Edmonton, Alberta (E.A.R.), CANADA



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Fig. 1. Partial correlations between blood HbA1c and the CV of starch intake (left) and between HbA1c and CV of diet glycemic index (GI; right) in 272 subjects with type 1 diabetes after adjusting for seven confounding variables (age, gender, duration of diabetes, insulin dose, height, weight and body mass index). Residuals are the differences between the observed values for HbA1c, CV starch and CV of diet GI and the values predicted from the confounding variables by multiple correlation analysis.

 


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Fig. 2. Examples of daily intakes of carbohydrate (top) and starch (middle) and diet glycemic index (bottom) for six days in subjects with CVs equivalent to the mean plus 1 SD (left) and the mean minus 1 SD (right).

 





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