Zinc and IGF-I Concentrations in Pregnant Women with Anemia before and after Supplementation with Iron and/or Zinc
Soroku Nishiyama, MD, FACN,
Kohji Kiwaki, MD,
Yoshinobu Miyazaki, MD and
Taiji Hasuda, MD
Department of Pediatrics, Kumamoto University, School of Medicine (S.N., K.K.), Kumamoto, JAPAN
Department of Obstetrics and Gynecology, Jikei Hospital (Y.M., T.H.), Kumamoto, JAPAN

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Fig. 1. Relationship between serum zinc levels and hemoglobin levels (left panel r=0.376, p<0.01) and numbers of RBC (right panel r=0.349, p<0.01) before treatment (therapy groups plus control group n=96).
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Fig. 2. Change in hemoglobin concentrations in pregnant women prescribed iron, zinc and iron plus zinc during eight weeks. Concentrations of hemoglobin significantly increased in pregnant women given iron plus zinc (p<0.01). + indicates mean±SD.
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Fig. 3. Relationship between increase in IGF-I and hemoglobin concentrations (left panel r=0.563, p<0.05) and increase in numbers of RBC (right panel r=0.747, p<0.01) in pregnant women given zinc only (group B, n=11).
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Fig. 4. Relationship between increase in IGF-I and hemoglobin concentrations (left panel r=0.431, p<0.01) and increase in numbers of RBC (right panel r=0.451, p<0.01) in pregnant women given zinc (group B plus C, n=28).
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Copyright © 1999 by the American College of Nutrition.