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Weight Loss is Correlated with an Improved Lipoprotein Profile in Obese Postmenopausal Women

School of Public Health, Loma Linda University, Loma Linda, California (Z.R.C.-M., W.P., R.C.E., B.D.)
Department of Physiology (T.G.L.) University of Arizona, Tucson, Arizona
Department Nutritional Sciences (P.M.R., W.H.H.), University of Arizona, Tucson, Arizona
Department of Nutritional Sciences, University of Connecticut, Storrs, Connecticut (J.R., M.L.F.)

View larger version (18K): [in a new window]   Fig. 1. Body weights of postmenopausal women during a six-month weight reduction program using Phentermine hydrochloride (Fastin®) plus 5040 kJ diet. Group I began treatment three months after Group II.

View larger version (39K): [in a new window]   Fig. 2. Percent of energy derived from carbohydrate, total fat and saturated fat in subjects from Group I (upper panel) and Group II (lower panel) over nine months. Group I began treatment three months after Group II. Different superscripts indicate significantly different over time.

View larger version (19K): [in a new window]   Fig. 3. Total fiber and dietary cholesterol (x10) in g/day fat in subjects from Group I (upper panel) and Group II (lower panel) over nine months. Group I began treatment three months after Group II. Different superscripts indicate significantly different over time.

View larger version (29K): [in a new window]   Fig. 4. Plasma concentrations of total cholesterol (TC; panel A), LDL cholesterol (LDL-C; panel B), HDL cholesterol (HDL-C; panel C) and triacylglycerol (TAG; panel D) of postmenopausal women during a six-month weight reduction program using Phentermine hydrochloride (Fastin®) plus 5040 kJ diet. Group I delayed initiation of treatment for three months (time period indicated as "Pre-"); Group II discontinued Phentermine hydrochloride after six months, but continued the 5040 kJ diet through nine months (time period indicated as "Post-").