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Effect of Triglyceride Structure on Fecal Excretion of 13C-Labeled Triglycerides

Sally A. Schuette, PhD, Morteza Janghorbani, PhD, Mitchell B. Cohen, MD, Susan Krug, MS, RD, Terri Schindler, RD, LD, David A. Wagner, PhD and Eugene P. DiMagno, MD

BioChemAnalysis Corp (S.A.S., M.J.), Chicago, Illinois
Center for Stable Isotope Research Inc (M.J.), Chicago, Illinois
Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio (M.B.C., S.K., T.S)
Metabolic Solutions Inc., Nashua, New Hampshire (D.A.W.)
Mayo Clinic and Foundation, Rochester, Minnesota (E.P.D.)



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Fig. 1. Correlation between P*P*P* (•), P*LP* ({blacksquare}{square}), and SO*S ({blacktriangleup}) excretion and stool fat for studies in which Dy excretion for the entire stool composite was >90%. All filled symbols represent tests carried out in CF patients whereas the open symbol ({square}) represents tests performed in patients with chronic pancreatitis. Excretion of all TG*s is expressed as percent of oral dose and all stool fat values as g/24 hours. Linear regression analysis was performed using SPSS Version 10 and the least squares fit line is shown for each TG*. The calculated regression parameters for each TG* are as follows: P*P*P* r2 = 0.941, slope = 3.20 and y-intercept = 9.04; P*LP* r2 = 0.924, slope 0.592 and y-intercept = 4.02; SO*S r2 = 0.845, slope = 0.120 and y-intercept = 0.900.

 





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