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In Vitro Application of Endotoxin to Thoracic Aortas from Magnesium-Deficient Rats Enhances Vascular Hyporeactivity to Phenylephrine

Atsushi Miyamoto, DVM, PhD, Hiroshi Moriki, DVM, Shigeru Ishiguro, DVM, PhD and Akira Nishio, DVM, PhD

Department of Veterinary Pharmacology, Faculty of Agriculture, Kagoshima University, Kagoshima, JAPAN



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  		Fig. 1. Effects of LPS on phenylephrine-induced contraction and acetylcholine-induced relaxation in thoracic aorta isolated from control and Mg-deficient rats.

 


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  		Fig. 2. Effects of 1400 W, ODQ and TEA on LPS (1 µg/mL)-induced hyporeactivity in thoracic aortas isolated from control and Mg-deficient rats. *Tension: mN/mg wet tissue.

 




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