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Magnesium Gluconate Offers No More Protection than Magnesium Sulphate Following Diffuse Traumatic Brain Injury in Rats

Renee J. Turner, BSc, K. W. DaSilva, C. O’Connor, Corinna van den Heuvel, PhD and Robert Vink, PhD

Department of Pathology, University of Adelaide, Adelaide SA, AUSTRALIA



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  		Fig. 1. Rotarod (motor) score after severe traumatic brain injury in rats. Treatment with either magnesium sulphate or magnesium gluconate resulted in a significant improvement in motor outcome relative to vehicle treated animals (p < 0.01).

 


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  		Fig. 2. H&E stained sections of the cortex after traumatic brain injury in rats. (A) Vehicle treated animal showing marked dark cell change and misshapen neurones; (B) magnesium gluconate treated animals; (C) magnesium sulphate treated animals.

 




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