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Enhancement of Absorption by Gum Arabic in a Model of Gastrointestinal Dysfunction

Champa N. Codipilly, PhD, Saul Teichberg, PhD and Raul A. Wapnir, PhD, FACN, CNS

Division of Neonatal/Perinatal Medicine, Schneider Children’s Hospital at North Shore (C.N.C.)
The Feinstein Institute for Medical Research, North Shore-Long Island Jewish Health System (S.T., R.A.W.), Manhasset, New York


Figure 1
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Fig. 1. Net water absorption rates in rats exposed for 6 days to either a cathartic mixture (PC), the same containing 10 g/L of GA (GA1), or 20 g/L GA (GA1). Control rats (CTL) were offered water, or water with 20 g/L GA (CTL + GA). Brackets represent the SEM. N = 14 for each group. The lettering on the bar signifies that those not sharing a letter are different (p < 0.05).

 

Figure 2
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Fig. 2. Sodium absorption under conditions similar to those described under Fig. 1 and for the same treatment groups. The boxes and the error brackets show the median, the 25/75, and the 10/90 percentiles. Significance of differences is indicated as in Fig. 1. Each group had 13 rats.

 

Figure 3
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Fig. 3. Glucose absorption rates for rats subjected to the treatment described under Fig. 1 and represented as indicated in the legend of Fig. 2 with the same number of animals than the latter.

 

Figure 4
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Fig. 4. NOS data for rats exposed for either 6 or 3 days to the treatments described under Fig. 1. N = 11–13 per group for the 6 day treatment; N = 9–12 per group for the 3 day treatment. Bars not labeled with the same letters are different (p < 0.05) signifying no differences between the PC, GA1 and GA2 groups, and higher activity than the CTL and CT + GA.

 





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